Wani bincike na Danish ya nuna cewa ga marasa lafiya da ke da mummunan cututtuka na cututtuka na huhu (COPD), amoxicillin kadai yana da sakamako mafi kyau fiye da amoxicillin tare da wani maganin rigakafi, clavulanic acid.
Binciken mai suna "Antibiotic Therapy in Acute Exacerbations of COPD: Sakamakon Marasa lafiya na Amoxicillin da Amoxicillin/Clavulanic Acid-Bayani daga marasa lafiya 43,636" an buga shi a cikin Journal of Respiratory Research.
Wani mummunan tashin hankali na COPD wani lamari ne wanda alamun majiyyaci ya kara tsananta ba zato ba tsammani. Tun da yake waɗannan abubuwan da suka fi muni yawanci suna da alaƙa da cututtukan ƙwayoyin cuta, jiyya tare da maganin rigakafi (magungunan da ke kashe ƙwayoyin cuta) wani ɓangare ne na daidaitattun kulawa.
A Denmark, akwai magungunan rigakafi guda biyu da aka saba amfani da su waɗanda za a iya amfani da su don magance irin wannan tashin hankali. Daya shine 750 MG amoxicillin sau uku a rana, ɗayan kuma shine 500 MG amoxicillin da clavulanic acid 125 mg, shima sau uku a rana.
Amoxicillin da clavulanic acid duka biyun beta-lactams ne, waɗanda maganin rigakafi ne waɗanda ke aiki ta hanyar tsoma baki tare da samar da bangon ƙwayoyin cuta, ta haka ne ke kashe ƙwayoyin cuta.
Babban ka'idar hada waɗannan maganin rigakafi guda biyu shine cewa clavulanic acid yana da tasiri akan ƙarin nau'ikan ƙwayoyin cuta. Duk da haka, magani tare da amoxicillin kadai yana nufin cewa ana iya ba da maganin rigakafi guda ɗaya a mafi girma, wanda zai iya kashe kwayoyin cutar da kyau.
Yanzu, ƙungiyar masu bincike na Danish kai tsaye sun kwatanta sakamakon waɗannan ka'idoji guda biyu don maganin mummunan tashin hankali na COPD.
Masu binciken sun yi amfani da bayanai daga rajistar COPD na Danish, haɗe tare da bayanai daga wasu rajista na ƙasa, don gano marasa lafiya 43,639 tare da mummunan yanayin da suka karbi daya daga cikin zaɓuɓɓuka biyu da aka bincika. Musamman, mutane 12,915 sun dauki amoxicillin kadai kuma mutane 30,721 sun sha magungunan hadewa. Ya kamata a lura cewa babu wani daga cikin marasa lafiya da aka bincikar da aka kwantar da su a asibiti saboda tsananin COPD, wanda ke nuna cewa harin ba shi da tsanani.
Idan aka kwatanta da haɗin amoxicillin da clavulanic acid, jiyya tare da amoxicillin kaɗai na iya rage haɗarin asibiti da ke da alaƙa da ciwon huhu ko kuma duk abin da ke haifar da mutuwa da kashi 40% bayan kwanaki 30. Amoxicillin kadai kuma yana da alaƙa da raguwar kashi 10 cikin 100 na haɗarin rashin asibiti ko mutuwar ciwon huhu da raguwar kashi 20% cikin haɗarin asibiti ko mutuwa.
Ga duk waɗannan matakan, bambanci tsakanin jiyya biyu yana da mahimmanci a ƙididdiga. Ƙarin bincike na ƙididdiga yawanci zai sami tabbataccen sakamako.
Masu binciken sun rubuta cewa: "Mun gano cewa idan aka kwatanta da AMC [amoxicillin da clavulanic acid], marasa lafiya na AECOPD [COPD exacerbation] da aka yi amfani da su tare da AMX [amoxicillin kadai] suna cikin haɗarin asibiti ko mutuwa tare da ciwon huhu a cikin kwanaki 30 Muhimmanci."
Tawagar ta yi hasashen cewa dalili daya da zai iya haifar da wannan sakamakon shine bambancin sashi tsakanin tsarin maganin rigakafi guda biyu.
"Lokacin da aka gudanar a daidai wannan kashi, AMC [haɗuwa] ba zai yiwu ya zama ƙasa da AMX [amoxicillin kadai] ba," sun rubuta.
Gabaɗaya, binciken "yana goyan bayan amfani da AMX a matsayin maganin rigakafi da aka fi so ga marasa lafiya tare da AECOPD," masu binciken sun kammala saboda "ƙarin clavulanic acid zuwa amoxicillin ba shi da alaƙa da sakamako mafi kyau."
A cewar masu binciken, babban ƙayyadaddun binciken shine haɗarin rikicewa saboda alamu-a wasu kalmomi, mutanen da suka riga sun kasance cikin rashin lafiya suna iya samun damar samun haɗin gwiwa. Kodayake ƙididdigar ƙididdiga na masu binciken sun yi ƙoƙarin bayyana wannan batu, har yanzu yana yiwuwa cewa bambance-bambancen da aka rigaya kafin magani sun bayyana wasu sakamakon.
Wannan gidan yanar gizon yanar gizon yanar gizon labarai ne da bayanai game da cutar. Ba ya bayar da shawarar likita, ganewar asali ko magani. Wannan abun ciki baya maye gurbin ƙwararrun shawarwarin likita, ganewar asali ko magani. Idan kuna da wasu tambayoyi game da yanayin kiwon lafiya, koyaushe nemi shawarar likitan ku ko wasu ƙwararrun ma'aikatan kiwon lafiya. Kada ku yi watsi da shawarwarin likita na ƙwararru ko jinkirta neman shawarar likita saboda abin da kuka karanta akan wannan rukunin yanar gizon.