Shekaru ashirin da suka wuce, an ba da albendazole ga wani babban shiri don maganin filariasis na lymphatic. Wani sabon bita na Cochrane yayi nazarin ingancin albendazole a cikin filariasis na lymphatic.
Lymphatic filariasis cuta ce da sauro ke haifar da ita wanda aka fi samu a yankuna masu zafi da na wurare masu zafi ta hanyar kamuwa da filariasis na parasitic. Bayan kamuwa da cuta, larvae suna girma zuwa manya da ma'aurata don samar da microfilariae (mf). Sannan sauro ne ke tattara MF yayin da ake ciyar da jini, kuma ana iya kamuwa da cutar zuwa wani mutum.
Ana iya gano cutar ta hanyar gwaje-gwaje don kewaya MF (microfilaremia) ko antigens parasites (antigenemia) ko ta hanyar gano tsutsotsi masu rai ta hanyar duban dan tayi.
Hukumar Lafiya ta Duniya (WHO) ta ba da shawarar a yi wa daukacin al’umma magani da yawa duk shekara har na tsawon akalla shekaru biyar. Tushen jiyya shine haɗin magunguna guda biyu: albendazole da microfilaricidal (antimalarial) miyagun ƙwayoyi diethylcarbamazine (DEC) ko ivermectin.
Albendazole na shekara-shekara ana ba da shawarar a wuraren da loiasis ke da alaƙa, kuma bai kamata a yi amfani da DEC ko ivermectin ba saboda haɗarin haɗari mai tsanani.
Dukansu ivermectin da DEK sun kawar da cututtukan mf da sauri kuma suna iya hana komawarsu. Koyaya, samar da mf zai ci gaba saboda ƙarancin fallasa a cikin manya. An yi la'akari da Albendazole don maganin filariasis na lymphatic saboda wani bincike ya ruwaito cewa yawan allurai da aka yi a cikin makonni da yawa ya haifar da mummunar illa da ke nuna mutuwar tsofaffin tsutsotsi.
Wani rahoto na yau da kullun na shawarwarin WHO daga baya ya nuna cewa albendazole yana da tasirin kisa ko fungicidal akan manya. A cikin 2000, GSK ta fara ba da gudummawar albendazole ga Shirin Jiyya na Filariasis na Lymphatic.
Gwajin gwaje-gwajen da aka bazu (RCTs) sun bincika inganci da amincin albendazole kadai ko a hade tare da ivermectin ko DEC. Wannan ya biyo bayan sake dubawa na tsari da yawa na RCTs da bayanan lura, amma ba a sani ba ko albendazole yana da wani fa'ida a cikin filariasis na lymphatic.
Dangane da wannan, an sabunta nazarin Cochrane da aka buga a cikin 2005 don tantance tasirin albendazole akan yawan jama'a da al'ummomin da ke da filariasis na lymphatic.