Streptomycin Sulfate: Cov tshuaj tua kab mob Aminoglycoside muaj zog hauv cov tshuaj niaj hnub no

Hauv thaj chaw ntawm cov tshuaj tua kab mob, Streptomycin Sulfate sawv tawm raws li kev txhim khu kev qha thiab muaj zog aminoglycoside uas tau ua haujlwm zoo hauv kev tawm tsam cov kab mob sib kis tau ntau xyoo. Qhov sib xyaw ua ke no muaj ntau yam, nrog nws cov txheej txheem tshwj xeeb ntawm kev ua, txuas ntxiv ua lub hauv paus hauv kev tiv thaiv kab mob thoob ntiaj teb.

Streptomycin Sulfate yog dab tsi?

Streptomycin Sulfate, coj tus lej CAS 3810-74-0, yog cov tshuaj tua kab mob aminoglycoside muab los ntawm Streptomyces griseus, cov kab mob hauv av. Nws yog tus cwj pwm los ntawm nws lub peev xwm los inhibit protein synthesis nyob rau hauv cov kab mob hlwb, zoo halting lawv txoj kev loj hlob thiab replication. Cov tshuaj tua kab mob no muaj nyob hauv ntau qib, suav nrog USP Qib, ua kom nws huv huv thiab tsim nyog rau kev siv kho mob.

Qhov tseem ceeb thiab kev siv

Qhov tseem ceeb ntawm Streptomycin Sulfate nyob rau hauv nws cov kev ua broad-spectrum tiv thaiv ntau Gram-negative thiab qee cov kab mob Gram-zoo. Nws yog tshwj xeeb tshaj yog zoo nyob rau hauv kev kho mob tuberculosis, ib tug kab mob sib kis uas muaj feem xyuam rau lub ntsws thiab lwm qhov chaw ntawm lub cev. Nws lub luag haujlwm hauv kev kho tuberculosis yog qhov tseem ceeb, feem ntau ua haujlwm ua ib feem ntawm kev sib xyaw ua ke los txhim kho kev ua tau zoo thiab tiv thaiv kev txhim kho kev tiv thaiv.

Ntxiv mus, Streptomycin Sulfate pom cov ntawv thov hauv cov tshuaj kho tsiaj, kev ua liaj ua teb, thiab kev tshawb fawb chaw. Hauv kev ua liaj ua teb, nws pab tswj cov kab mob kab mob hauv cov qoob loo thiab cov tsiaj nyeg, txhim kho cov qoob loo thiab cov tsiaj noj qab haus huv. Cov kws tshawb fawb kuj tseem siv Streptomycin Sulfate los kawm txog kab mob caj ces, tshuaj tua kab mob, thiab cov txheej txheem tsim cov protein.

Mechanism ntawm Action

Lub tshuab uas Streptomycin Sulfate exerts nws antibacterial nyhuv cuam tshuam nrog cov kab mob protein synthesis. Tshwj xeeb, nws khi rau cov kab mob ribosome, cuam tshuam rau kev xaiv hloov RNA (tRNA) thaum lub sijhawm txhais lus. Qhov kev sib khi no cuam tshuam qhov tseeb ntawm kev txiav txim siab mRNA los ntawm ribosome, ua rau kev tsim cov proteins uas tsis ua haujlwm lossis raug txiav. Yog li ntawd, cov kab mob ntawm tes tsis tuaj yeem txhawb nqa nws txoj haujlwm tseem ceeb, thaum kawg ua rau cell tuag.

Interestingly, Streptomycin Sulfate kuj feem ntau qhia txog kev hloov pauv hauv ribosomal protein S12. Cov kev hloov pauv no ua rau pom muaj kev ntxub ntxaug ntau ntxiv thaum xaiv tRNA, ua rau lawv tsis tshua muaj kev cuam tshuam rau cov tshuaj tua kab mob. Kev nkag siab txog cov txheej txheem tiv thaiv no yog qhov tseem ceeb rau kev tsim cov tswv yim kho tshiab thiab tiv thaiv cov kev hem thawj ntawm cov tshuaj tiv thaiv kab mob.

Cia thiab tuav
Tsim nyog
khaws cia thiab tuav ntawm Streptomycin Sulfate yog qhov tseem ceeb los tswj nws txoj kev ua tau zoo thiab kev nyab xeeb. Cov tshuaj tua kab mob no yuav tsum tau khaws cia ntawm qhov kub ntawm 2-8 ° C (36-46 ° F) hauv lub thawv kaw, kom deb ntawm noo noo thiab lub teeb. Cov xwm txheej no pab khaws cia lub compound stability thiab tiv thaiv degradation.

Kev Ua Lag Luam thiab Muaj

Streptomycin Sulfate yog dav muaj nyob rau hauv khw muag tshuaj, muaj los ntawm ntau manufacturers thiab lwm tus neeg nyob rau hauv lub ntiaj teb no. Cov nqi yuav txawv nyob ntawm seb yam xws li qib, purity, thiab kom muaj nuj nqis. High-zoo Streptomycin Sulfate, xws li qhov ua tau raws li USP cov qauv, hais kom tus nqi them vim nws qhov kev sim nruj thiab kev ruaj ntseg ntawm purity.

Yav tom ntej Prospects

Txawm hais tias nws muaj keeb kwm ntev ntawm kev siv, Streptomycin Sulfate tseem yog ib qho tshuaj tua kab mob tseem ceeb hauv kev tawm tsam cov kab mob. Raws li cov kws tshawb fawb txuas ntxiv tshawb nrhiav cov tshuaj tua kab mob tshiab thiab cov tswv yim kho mob, Streptomycin Sulfate lub luag haujlwm yuav hloov zuj zus. Txawm li cas los xij, nws txoj kev ua tau zoo, kev ua haujlwm dav dav, thiab tus nqi qis ua rau nws muaj txiaj ntsig zoo hauv ntau qhov chaw kho mob thiab kev tshawb fawb.

Hauv kev xaus, Streptomycin Sulfate yog ib qho pov thawj rau lub zog ntawm cov tshuaj tua kab mob hauv cov tshuaj niaj hnub. Nws lub peev xwm los cuam tshuam cov kab mob protein synthesis thiab tiv thaiv kab mob tau cawm ntau tus neeg txoj sia thiab tseem ua lub hauv paus hauv kev kho mob tiv thaiv kab mob. Nrog rau kev tshawb fawb tsis tu ncua thiab txhim kho cov tshuaj tua kab mob tshiab, Streptomycin Sulfate cov keeb kwm yuav ua rau muaj kev ntxhov siab, pab txhawb rau lub ntiaj teb kev siv zog los tawm tsam cov kab mob sib kis.