Ruo afọ iri abụọ, e nyela albendazole n'ọtụtụ mmemme maka ọgwụgwọ lymphatic filariasis. Nyocha Cochrane emelitere nyochara nrụpụta albendazole na lymphatic filariasis.
Lymphatic filariasis bụ ọrịa anwụnta na-ebutekarị na mpaghara okpomọkụ na mpaghara ebe okpomọkụ nke nje filariasis na-akpata. Mgbe ọrịa gasịrị, larvae na-etolite ghọọ ndị okenye na di na nwunye na-etolite microfilariae (mf). A na-anakọta MF site na anwụnta mgbe ọ na-eri ọbara, enwere ike ibunye ọrịa ahụ na onye ọzọ.
Enwere ike ịchọpụta ọrịa site na nyocha maka ịgbasa MF (microfilaremia) ma ọ bụ antigens parasite (antigenemia) ma ọ bụ site na nchọpụta nke ikpuru ndị okenye dị ndụ site na ultrasound.
Òtù Ahụ Ike Ụwa (WHO) na-atụ aro ka a na-emeso ndị mmadụ n'ọtụtụ ebe kwa afọ ma ọ dịkarịa ala afọ ise. Ndabere nke ọgwụgwọ bụ ngwakọta nke ọgwụ abụọ: albendazole na microfilaricidal (antimalarial) ọgwụ diethylcarbamazine (DEC) ma ọ bụ ivermectin.
A na-atụ aro Albendazole kwa afọ na mpaghara ebe loiasis na-ejikọta ya, na e kwesịghị iji DEC ma ọ bụ ivermectin n'ihi ihe ize ndụ nke mmetụta ọjọọ.
Ma ivermectin na DEK kpochapụrụ ọrịa mf ngwa ngwa ma nwee ike igbochi nlọghachi ha. Agbanyeghị, mmepụta mf ga-amaliteghachi n'ihi oke ikpughe na ndị okenye. A na-atụle Albendazole maka ọgwụgwọ lymphatic filariasis n'ihi na otu nnyocha kwuru na nnukwu doses a na-enye n'ime izu ole na ole kpatara mmetụta dị njọ na-egosi ọnwụ nke ikpuru ndị toro eto.
Otu akụkọ na-edoghị anya nke ndụmọdụ WHO mechara tụọ aro na albendazole nwere mmetụta igbu mmadụ ma ọ bụ fungicidal na ndị okenye. N'afọ 2000, GSK malitere inye albendazole na mmemme ọgwụgwọ Lymphatic Filariasis.
Nnwale ụlọ ọgwụ a na-ahaziri (RCT) enyochala ịdị mma na nchekwa nke albendazole naanị ma ọ bụ yana yana ivermectin ma ọ bụ DEC. Nke a sochiri ọtụtụ nyocha usoro nke RCT na data nyocha, mana amabeghị ma albendazole nwere uru ọ bụla na lymphatic filariasis.
N'iburu nke a, a na-emelite nyocha Cochrane nke e bipụtara na 2005 iji chọpụta mmetụta albendazole na ndị mmadụ na obodo nwere lymphatic filariasis.