l: A Versatile Antibiotic for Various Applications

In the realm of antibiotics, Oxytetracycline HCl has emerged as a pivotal compound due to its broad-spectrum antibacterial properties and versatility in various applications. Recently, this compound has garnered significant attention from both the scientific community and industrial sectors, making it a subject of rigorous research and commercial interest.

Oxytetracycline HCl, with its chemical formula C22H24N2O9·HCl and a molecular weight of 496.89, is a yellow crystalline powder that is stable in air but can darken under exposure to sunlight. This antibiotic belongs to the tetracycline class of drugs and functions by inhibiting protein synthesis through preventing the binding of aminoacyl-tRNA to the 30S ribosomal subunit. Its broad-spectrum activity covers both Gram-positive and Gram-negative bacteria, making it a valuable tool in both research and practical applications.

The antibiotic is known for its effectiveness in various animal health scenarios. A study published in Poultry Science in 1977 investigated the pharmacodynamics of oxytetracycline HCl in chickens. The research found that both oral and intramuscular administration routes were effective, with intramuscular and subcutaneous routes resulting in higher tissue levels. Notably, kidney and liver samples contained the highest levels of the drug, whereas lung and serum levels were generally low. This research underscores the importance of appropriate administration routes in ensuring effective drug delivery.

In addition to its animal health applications, Oxytetracycline HCl is also widely used in agricultural feed to promote growth and prevent infections. For instance, in pig feed, it is used at specific dosages depending on the age of the pigs. Similarly, in chicken feed, it is added to enhance growth and health, albeit with restrictions during the laying period. These applications reflect the compound's efficacy and versatility in animal husbandry.

The industrial production and commercial availability of Oxytetracycline HCl have expanded significantly. Several companies, such as Shanghai Zeye Biotechnology Co., Ltd., offer this product in various specifications and quantities. These companies typically ensure high purity levels, often exceeding 95% (HPLC), and provide detailed product specifications, including CAS numbers, molecular weights, and storage conditions. With operations rooted in research and development, these companies continuously strive to enhance product quality and expand their product lines to meet evolving market demands.

The increasing commercial availability of Oxytetracycline HCl has also fueled research into its potential applications beyond traditional uses. In biochemical research, the compound serves as a valuable tool for studying protein synthesis and ribosomal function. Its ability to specifically target bacterial ribosomal subunits makes it an attractive candidate for further development in the field of antibacterial drug discovery.

Moreover, the use of Oxytetracycline HCl in electrophoresis experiments demonstrates its application in molecular biology research. Its specific interactions with DNA and electrophoresis buffers make it a useful reagent for studying DNA migration patterns and band formations. These studies contribute to advancing our understanding of molecular mechanisms and facilitate the development of new diagnostic techniques.

In conclusion, Oxytetracycline HCl stands as a testament to the continued evolution and advancement of antibiotic technology. Its broad-spectrum antibacterial activity, coupled with its versatility in various applications, underscores its significance in both research and practical settings. As companies continue to enhance production methods and expand product offerings, the potential applications of Oxytetracycline HCl are likely to grow, further cementing its status as a cornerstone in the field of antibiotics.