Cimetidine ndi mankhwala omwe amalepheretsa kupanga asidi ndi maselo otulutsa asidi m'mimba ndipo amatha kuperekedwa pakamwa, IM kapena IV.

Cimetidine amagwiritsidwa ntchito:

• chepetsakutentha pamtimazogwirizana ndiacid kudzimbidwandi mimba yowawa
• kupewa kutentha pamtima komwe kumadza chifukwa cha kudya kapena kumwa zakudya zina ndizakumwa

Iwo ndi a gulu lamankhwalaotchedwa H2 (histamine-2) blockers omwe amaphatikizansoranitidine(Zantac),nizatidine(Axid), ndifamotidine(Pepcid). Histamine ndi mankhwala omwe amapezeka mwachilengedwe omwe amalimbikitsa ma cell a m'mimba (ma cell a parietal) kupanga asidi. H2-blockers amalepheretsa zochita za histamine m'maselo, motero amachepetsa kupanga kwa asidi m'mimba.

Chifukwa asidi m'mimba akhoza kuwonongakummero, m'mimba, ndi duodenum ndi reflux ndi kuchititsa kutupa ndi zilonda, kuchepetsa asidi m'mimba kumateteza ndi kulola kuti asidi-omwe kutupa ndi zilonda kuchira. Cimetidine idavomerezedwa ndi FDA mu 1977.