Coadministration ya ivermectin, diethylcarbamazine, na albendazole itanga imiti myinshi ya farumasi

kumenyekanisha:

Mu iterambere ryibikorwa byubuzima rusange, abashakashatsi bemeje umutekano n’ingirakamaro by’imiti minini ihuza imiti ya ivermectin, diethylcarbamazine (DEC) na albendazole. Iri terambere rikomeye rizagira ingaruka cyane kubikorwa byisi byo kurwanya indwara zitandukanye zo mu turere dushyuha (NTD).

inyuma:

Indwara zo mu turere dushyuha zireba abantu barenga miliyari imwe mu bihugu bikennye kandi bitera ibibazo bikomeye ku buzima bw'isi. Ivermectin ikoreshwa cyane mu kuvura indwara zanduye, harimo n'ubuhumyi bw'inzuzi, mu gihe DEC yibasira lymphatic filariasis. Albendazole ifite akamaro mukurwanya inyo zo munda. Gufatanya hamwe nibi biyobyabwenge birashobora gukemura icyarimwe NTD icyarimwe, bigatuma uburyo bwo kuvura bukora neza kandi buhendutse.

Umutekano no gukora neza:

Ubushakashatsi buherutse gukorwa nitsinda ryabashakashatsi mpuzamahanga bugamije gusuzuma umutekano wo gufata ibiyobyabwenge bitatu hamwe. Urubanza rwitabiriwe n'abantu barenga 5.000 mu bihugu byinshi, harimo n'abafite ubwandu. Ibyavuye mu bushakashatsi byagaragaje ko kuvura hamwe byihanganirwa kandi bifite ingaruka mbi nkeya. Icyitonderwa, ubwinshi nuburemere bwibintu bibi byasa nkibyagaragaye mugihe buri muti wafashwe wenyine.

Byongeye kandi, imikorere yimiti minini ihuza ibiyobyabwenge irashimishije. Abitabiriye amahugurwa bagaragaje ko bagabanutse cyane ku mutwaro wa parasite ndetse banateza imbere ivuriro ry’indwara zavuwe. Igisubizo nticyerekana gusa ingaruka ziterwa no kuvura hamwe ahubwo gitanga nibindi bimenyetso byerekana ko bishoboka kandi birambye gahunda zuzuye zo kugenzura NTD.

Ingaruka ku buzima rusange:

Gushyira mu bikorwa neza imiti ikomatanya bizana ibyiringiro byinshi mubikorwa binini byo kuvura ibiyobyabwenge. Muguhuza imiti itatu yingenzi, izi gahunda zirashobora koroshya imikorere no kugabanya ibiciro hamwe nibikoresho bigoye bijyanye no gukora gahunda zitandukanye zo kuvura. Byongeye kandi, kongera imikorere no kugabanya ingaruka zituma ubu buryo bukundwa cyane, bigatuma habaho kubahiriza neza muri rusange.

Intego zo kurandura isi yose:

Ihuriro rya ivermectin, DEC na albendazole rijyanye n’inzira y’umuryango w’ubuzima ku isi (OMS) yo gukuraho NTDs. Intego z'iterambere rirambye (SDGs) zirasaba kurwanya, kurandura cyangwa kurandura burundu izo ndwara mu 2030. Ubu buryo bwo kuvura bwerekana intambwe y'ingenzi iganisha kuri izo ntego, cyane cyane mu turere usanga NTD nyinshi zibana.

ibyiringiro:

Intsinzi yubu bushakashatsi ifungura inzira yo kwagura ingamba zo kuvura. Kuri ubu abashakashatsi barimo gukora ubushakashatsi ku bushobozi bwo kwinjiza indi miti yihariye ya NTD mu buvuzi buvanze, nka praziquantel ya schistosomiasis cyangwa azithromycine ya trachoma. Izi ngamba zerekana umuryango wubumenyi wiyemeje gukomeza guhuza no guteza imbere gahunda yo kugenzura NTD.

Inzitizi n'imyanzuro:

Nubwo coadministration ya ivermectin, DEC, na albendazole itanga inyungu zifatika, ibibazo biracyahari. Guhuza ubwo buryo bwo kuvura mubice bitandukanye by’akarere, kwemeza ko bigerwaho, no gutsinda inzitizi z’ibikoresho bizasaba imbaraga z’ubufatanye hagati ya guverinoma, imiryango mpuzamahanga, n’abatanga ubuvuzi. Nyamara, ubushobozi bwo kuzamura umusaruro wubuzima rusange bwabantu babarirwa muri za miriyari burenze kure izo mbogamizi.

Mu gusoza, guhuza neza ivermectin, DEC, na albendazole bitanga igisubizo gifatika kandi cyizewe cyo kuvura indwara nini zo mu turere dushyuha. Ubu buryo bwuzuye bufite amasezerano akomeye yo kugera ku ntego zo kurandura isi kandi bugaragaza ubwitange bwa siyanse mu gukemura ibibazo by’ubuzima rusange. Hamwe nubushakashatsi nibindi bikorwa, ejo hazaza h'igenzura rya NTD bigaragara neza kurusha mbere.