Cimetidine ni umuti uhagarika umusaruro wa aside ukoresheje selile zitanga aside mu gifu kandi zishobora gutangwa mu kanwa, IM cyangwa IV.

Cimetidine ikoreshwa kuri:

• humuragutwikabifitanye isano naaside indigestionn'inda ikarishye
• irinde gutwikwa kuzanwa no kurya cyangwa kunywa ibiryo bimwe naibinyobwa

Ni icyiciro cyaibiyobyabwengebita H2 (histamine-2) ibibuza nabyo birimorunitidine(Zantac),nizatidine(Axid), nafamotidine(Pepcid). Histamine ni imiti isanzwe ibaho itera ingirabuzimafatizo mu gifu (parietal selile) kubyara aside. H2-blokers ibuza ibikorwa bya histamine kuri selile, bityo bikagabanya umusaruro wa aside ukoresheje igifu.

Kubera ko aside igifu ikabije ishobora kwangizaesofagus, igifu, na duodenum byongeye kandi biganisha ku gutwika no gukomeretsa, kugabanya aside igifu birinda kandi bigatuma aside iterwa na aside hamwe n'ibisebe bikira. Cimetidine yemejwe na FDA mu 1977.