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Short Lead Time for Oxytetracycline Hcl 20% Powder - Tolterodine Tartrate – Tecsun

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  • Short Lead Time for Oxytetracycline Hcl 20% Powder - Tolterodine Tartrate – Tecsun

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Appearance White or almost white crystalline powder ,odourless. Solubility  Sparingly soluble in methonal, slightly soluble inwater, pratically insoluble in chloroform Melting point 205~ 2 10 ºC ,decomposed during the melting process Specific rotation + 27.0º~+ 30.0º Identification Chemical reaction Solution appears purpureal Characteristic absorption Exhibits a maximum at 282nm IR The IR absorption spectrum of tolterodin tartrate should concordant with that (IR Album N...


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Abamectin Benzoate , Oxytetracycline Hcl 20% Powder , Tylosin Doxycycline Tartrate ,
Short Lead Time for Oxytetracycline Hcl 20% Powder - Tolterodine Tartrate – Tecsun Detail:

Appearance White or almost white crystalline powder ,odourless.
Solubility  Sparingly soluble in methonal, slightly soluble inwater, pratically insoluble in chloroform
Melting point 205~ 2 10 ºC ,decomposed during the melting process
Specific rotation + 27.0º~+ 30.0º
Identification
Chemical reaction Solution appears purpureal
Characteristic absorption Exhibits a maximum at 282nm
IR The IR absorption spectrum of tolterodin tartrate should concordant with that (IR Album No.1037)of reference substance
Silver mirror reaction of tartrate Add liquid ammonia with silver nitrateseveral drops, put it in the water bath andheat, silver dissociates and attaches to theinner wall of the tube, a silver mirror forms
Test
Acidity PH:3.0-4.5
Lhloride Should not more intense than a referencesolution using 2.0ml of
sodium chloride standard solution (0.025%)
Sulfate Should not more intense than a referencesolution using 1.0ml of
potassium sulphate standard solution(0.05%)
Laevo isomer NMT1.0%
Related substances Any other single impurity :NMT0.1%
Total impurities:NMT 0.5%
Function Tolterodine is a competitive M receptor antagonist, and its selectivity to the bladder is significantly stronger than that of the salivary gland. Its inhibition of bladder contraction is about 20 times that of the salivary gland. After oral administration of tolterodine, the main active metabolite 5-hydroxymethyl derivative (DD01) produced by the liver is similar to the parental antimuscarinic activity and has significant therapeutic significance. Both have little affinity for other neurotransmitter receptors and potential cellular targets such as calcium channels.

 

 

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