Labaatan sano, albendazole waxaa lagu deeqay barnaamij baaxad leh oo loogu talagalay daawaynta lymfatic filariasis. Dib u eegis cusub oo Cochrane ah ayaa baadhay waxtarka albendazole ee filariasis lymphatic.
Lymphatic filariasis waa cudur ay kaneecadu ka dhalato sida caadiga ah laga helo gobollada kulaylaha iyo kulaylaha hoose ee ay keento caabuqa filariasis dulin. Infekshanka ka dib, dirxiyadu waxay u koraan qaangaar iyo lammaane si ay u sameeyaan microfilariae (mf). MF ka dib waxaa aruuriya kaneecada marka ay quudineyso dhiiga, infekshanka waxaa loo gudbin karaa qof kale.
Caabuqa waxaa lagu ogaan karaa baaritaanada wareegga wareegga MF (microfilaremia) ama antigens parasite (antigenemia) ama ogaanshaha gooryaanka qaangaarka nool ee ultrasound.
Ururka Caafimaadka Adduunka (WHO) waxa uu ku talinayaa in dadka oo dhan lagu daweeyo ugu yaraan shan sano sannadkii. Saldhigga daawaynta waa isku-darka laba daawo: albendazole iyo microfilaricidal (antimalarial) daroogada diethylcarbamazine (DEC) ama ivermectin.
Albendazole semi-sanad kasta waxaa lagula taliyaa meelaha loiasis-ku ka wada tirsan yahay, iyo DEC ama ivermectin waa inaan la isticmaalin khatarta waxyeellooyin halis ah awgeed.
Ivermectin iyo DEK labaduba waxay si dhakhso ah u nadiifiyeen caabuqyada mf waxayna joojin karaan soo noqoshada. Si kastaba ha ahaatee, wax soo saarka mf ayaa dib u bilaaban doona sababtoo ah soo-gaadhista xaddidan ee dadka waaweyn. Albendazole waxaa loo tixgeliyey daawaynta lymfatic filariasis sababtoo ah daraasad ayaa sheegtay in qiyaaso badan oo la bixiyay dhowr toddobaad ay keentay saameyno halis ah oo soo jeedinaya dhimashada gooryaanka qaangaarka ah.
Warbixin aan rasmi ahayn oo la talinta WHO ayaa dabadeed soo jeedisay in albendazole ay saameyn dil ah ama fungicidal ku leedahay dadka waaweyn. Sannadkii 2000, GSK waxa ay bilawday in ay ku tabarucdo albendazole Barnaamijka Daaweynta Filariasis ee Lymphatic.
Tijaabooyin caafimaad oo la kala soocay (RCTs) ayaa baadhay waxtarka iyo badbaadada albendazole oo keliya ama marka lagu daro ivermectin ama DEC. Tan waxaa soo raacay dhowr dib-u-eegis nidaamsan oo RCTs ah iyo xogta fiirsashada, laakiin ma cadda in albendazole uu wax faa'iido ah u leeyahay filariasis lymphatic.
Marka la eego tan, dib u eegista Cochrane ee la daabacay 2005 ayaa la cusbooneysiiyay si loo qiimeeyo saameynta albendazole ee dadka iyo bulshooyinka qaba filariasis lymphatic.