Streptomycin Sulfate: Antibiotic e Matla ea Aminoglycoside ho Meriana ea Kajeno

Sebakeng sa lithibela-mafu, Streptomycin Sulfate e hlahella e le aminoglycoside e ka tšeptjoang le e matla e 'nileng ea thusa ho loantša tšoaetso ea baktheria ka lilemo tse mashome. Motsoako ona o sebetsang ka mefuta-futa, o nang le mekhoa e ikhethang ea ts'ebetso, o ntse o tsoela pele ho ba motheo oa liphekolo tse thibelang tšoaetso lefatšeng ka bophara.

Streptomycin Sulfate ke eng?

Streptomycin Sulfate, e nang le nomoro ea CAS 3810-74-0, ke lithibela-mafu tsa aminoglycoside tse nkiloeng ho Streptomyces griseus, baktheria ea mobu. E tšoauoa ka bokhoni ba eona ba ho thibela protheine synthesis liseleng tsa baktheria, ka katleho e emisa kholo ea tsona le ho ikatisa. Sethibela-mafu sena se fumaneha lihlopheng tse fapaneng, ho kenyeletsoa USP Grade, ho netefatsa bohloeki ba eona le ho tšoaneleha bakeng sa tšebeliso ea bongaka.

Bohlokoa le Lisebelisoa

Bohlokoa ba Streptomycin Sulfate bo ho ts'ebetso ea eona e pharalletseng khahlano le libaktheria tse ngata tsa Gram-negative le tse ling tsa gram-positive. E sebetsa ka ho khetheha ho phekoleng lefuba, lefu le tšoaetsanoang le sa foleng le amang matšoafo le likarolo tse ling tsa ’mele. Karolo ea eona kalafong ea lefuba e bile ea bohlokoa, hangata e sebetsa e le karolo ea liphekolo tse kopaneng ho matlafatsa ts'ebetso le ho thibela nts'etsopele ea ho hanyetsa.

Ho feta moo, Streptomycin Sulfate e fumana lits'ebetso ho bongaka ba liphoofolo, temo le liphuputsong tsa lipatlisiso. Temong, e thusa ho laola mafu a baktheria lijalong le liphoofolong, ho matlafatsa chai le bophelo ba liphoofolo. Bafuputsi ba boetse ba sebelisa Streptomycin Sulfate ho ithuta ka liphatsa tsa lefutso tsa baktheria, lithibela-mafu tse hanyetsang, le mekhoa ea ho kopanya liprotheine.

Mokhoa oa Ts'ebetso

Mochine oo Streptomycin Sulfate e sebetsang ka oona oa antibacteria o kenyelletsa ho kena-kenana le motsoako oa protheine ea baktheria. Ka ho khetheha, e tlama ho ribosome ea baktheria, e amang khetho ea ho fetisa RNA (tRNA) nakong ea phetolelo. Tlamahano ena e sitisa ho nepahala ha ho hlakisa mRNA ka ribosome, e lebisang tlhahisong ea liprotheine tse sa sebetseng kapa tse fokolang. Ka lebaka leo, sele ea baktheria ha e khone ho ntšetsa pele mesebetsi ea eona ea bohlokoa, e leng ho fellang ka ho shoa ha lisele.

Ho khahlisang, khanyetso ea Streptomycin Sulfate hangata e bonts'a liphetoho tsa protheine ea ribosomal S12. Mefuta ena e fetotsoeng e bonts'a matla a phahameng a khethollo nakong ea khetho ea tRNA, e etsang hore li se ke tsa hlaseloa ke litlamorao tsa lithibela-mafu. Ho utloisisa mekhoa ena ea ho hanyetsa ke habohlokoa bakeng sa ho hlahisa mekhoa e mecha ea phekolo le ho loantša tšokelo e tsoelang pele ea ho hanyetsa lithibela-mafu.

Polokelo le Ho Tšoara
E nepahetseng
ho boloka le ho sebetsana le Streptomycin Sulfate ho bohlokoa ho boloka ts'ebetso le polokeho ea eona. Sethibela-mafu sena se lokela ho bolokoa mochesong o pakeng tsa 2-8°C (36-46°F) ka sejaneng se tiisitsoeng, hole le mongobo le khanya. Maemo ana a thusa ho boloka botsitso ba motsoako le ho thibela ho senyeha.

Mmaraka le ho fumaneha

Streptomycin Sulfate e fumaneha hohle 'marakeng oa meriana, e fanoang ke bahlahisi ba bangata le barekisi lefatšeng ka bophara. Litheko li ka fapana ho ea ka lintlha tse kang kereiti, ho hloeka, le bongata bo odatsoeng. Streptomycin Sulfate ea boleng bo holimo, joalo ka e fihlelang litekanyetso tsa USP, e laela tefiso ka lebaka la tlhahlobo ea eona e matla le tiisetso ea bohloeki.

Ditebello Tsa Bokamoso

Ho sa tsotellehe histori ea nako e telele ea tšebeliso, Streptomycin Sulfate e ntse e le lithibela-mafu tsa bohlokoa ntoeng khahlanong le tšoaetso ea baktheria. Ha bafuputsi ba ntse ba tsoela pele ho hlahloba lithibela-mafu tse ncha le mekhoa ea phekolo, karolo ea Streptomycin Sulfate e ka 'na ea fetoha. Leha ho le joalo, ts'ebetso ea eona e tiileng, ts'ebetso e pharalletseng, le litšenyehelo tse tlase li e etsa khetho ea bohlokoa maemong a mangata a bongaka le lipatlisiso.

Qetellong, Streptomycin Sulfate ke bopaki ba matla a lithibela-mafu meriana ea kajeno. Bokhoni ba eona ba ho thibela motsoako oa liprotheine tsa baktheria le ho loantša tšoaetso e pholositse bophelo bo se nang palo 'me e ntse e tsoela pele ho ba motheo oa liphekolo tse thibelang tšoaetso. Ka lipatlisiso tse tsoelang pele le nts'etsopele ea lithibela-mafu tse ncha, ha ho pelaelo hore lefa la Streptomycin Sulfate le tla tšoarella, ho kenya letsoho boitekong ba lefats'e ba ho loantša mafu a tšoaetsanoang.