I-Cimetidine isidakamizwa esivimbela ukukhiqizwa kwe-asidi ngamaseli akhiqiza i-asidi esiswini futhi ingasetshenziswa ngomlomo, i-IM noma i-IV.

I-Cimetidine isetshenziselwa:

• khululaisilungulelaehambisana neukuntuleka kwe-asidinesisu esimuncu
• vimbela isilungulela esilethwa ukudla noma ukuphuza ukudla okuthile futhiiziphuzo

Kungokwesigabaizidakamizwaebizwa ngokuthi i-H2 (histamine-2) blockers ehlanganisai-ranitidine(Zantac),i-nizatidine(I-axid), futhii-famotidine(I-Pepcid). I-Histamine iyikhemikhali eyenzeka ngokwemvelo eshukumisa amaseli esiswini (amangqamuzana e-parietal) ukuthi akhiqize i-asidi. Ama-H2-blockers avimbela ukusebenza kwe-histamine kumaseli, ngaleyo ndlela anciphise ukukhiqizwa kwe-asidi yisisu.

Njengoba i-asidi yesisu ngokweqile ingalimaza i-umphimbo, isisu, kanye ne-duodenum nge-reflux futhi kuholele ekuvuvukeni nasekuvuvukeni, ukunciphisa i-asidi yesisu kuvimbela futhi kuvumela ukuvuvukala okubangelwa i-asidi kanye nezilonda ukuba ziphole. I-Cimetidine yamukelwa yi-FDA ngo-1977.